Objective: This review examines various aspects of vitamin E, both in plant metabolism and
with regard to its importance for human health. Vitamin E is the collective name of a group of lipidsoluble
compounds, chromanols, which are widely distributed in the plant kingdom. Their biosynthetic
pathway, intracellular distribution and antioxidant function in plants are well recognized, although
their other functions are also considered.
Conclusion: Analytical methods for the determination of vitamin E are discussed in detail. Furthermore,
the vitamin E metabolism and its antioxidant action in humans are described. Other nonantioxidant
functions of vitamin E are also presented, such as its anti-inflammatory effects, role in the
prevention of cardiovascular diseases and cancer, as well as its protective functions against neurodegenerative
and other diseases.
Keywords: Antioxidants, diseases, oxidative stress, reactive oxygen species, tocopherols, tocopherol transfer protein, tocotrienols,
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