Objective: The spirooxindole heterocyclic scaffold is found in many natural products and
has been identified as an important bioactive agent.
Background: Over the past few decades, various spirooxindole-containing compounds have been
reported to possess biological properties and hence found in the structure of many synthetic pharmaceuticals.
This mini-review describes the most promising examples of this class of compounds possessing
biological activity including anticancer, anti-inflammatory, and antimicrobial activities.
Conclusion: The current review focuses on the biological activity of compounds containing the spirooxindole