Suzuki-Miyaura Cross-Coupling Reaction Catalyzed by Supported Palladium Under Microwave Irradiation

Author(s): Qing Han Li, Yong Ding, Gang Zhang, Zhen Zhang, Song Mo

Journal Name: Current Organic Synthesis

Volume 14 , Issue 3 , 2017

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Graphical Abstract:


Organic synthesis efficiency can take considerable advantage from microwave heating. Compared to conventional heating, it allows to improve the reactions speed and yield through an energy-efficient, clean, and easy-to-use processing tool. Transition-metal catalyzed cross-coupling reactions and in particular the Suzuki- Miyaura cross-coupling is powerful and widely used tool for the formation of carbon-carbon bonds. Crosscoupling reactions are of large interest for the bonding of a broad range of functional groups, in particular biaryl groups, allowing for a strong stereoselectivity. In this paper, recent research results concerning the application of microwave heating in Suzuki-Miyaura cross-coupling reactions are reviewed with particular emphasis on reactions involving supported Pd as a catalyst.

Keywords: Microwave chemistry, Suzuki-Miyaura reaction, supported palladium, C-C bond formation, organoboron compounds, crosscoupling.

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Article Details

Year: 2017
Page: [462 - 476]
Pages: 15
DOI: 10.2174/1570179413666160624092044
Price: $65

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