Targeting Cancer Cells with Photoactive Silica Nanoparticles

Author(s): Wioleta Borzęcka, Tito Trindade, Tomás Torres, João Tomé

Journal Name: Current Pharmaceutical Design

Volume 22 , Issue 39 , 2016

Become EABM
Become Reviewer
Call for Editor


This review highlights recent advances in the preparation of silica nanoparticles (SNPs) functionalized with porphyrins and phthalocyanines for application in cancer photodiagnostic and photodynamic therapy (PDT). The use of photosensitizer-SNP formulations has emerged recently as a new nanomedicine for cancer research owing to their unique physicochemical properties, which make them useful for photo-biomedical applications. In order to study their photobiological properties, diverse chemical strategies involving covalent and non-covalent bonding have been used to load photosensitizers in/on SNPs.

Keywords: Porphyrins, Phthalocyanines, Photosensitizers, Silica Nanoparticles, PDT, Cancer.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2016
Page: [6021 - 6038]
Pages: 18
DOI: 10.2174/1381612822666160614083804
Price: $65

Article Metrics

PDF: 29