Frontiers in Cancer Immunology

Volume: 2

Systems Biology in Cancer Immunotherapy

Indexed in: EBSCO.

Over the past decades, systems biology approaches have been applied in different areas of life science research including oncology. Researchers now understand the hallmarks of cancer cells such as ...
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Cancer Immunotherapy

Pp. 86-121 (36)

Mahbuba Rahman

Abstract

Treatment of cancer does not depend on a single drug and the existing strategies are challenged by the the frequent development of drug resistance properties of cancer cells. Although chemotherapy drugs are still used as the first line of treatment modalities for cancer, immunotherapyis also used as a targeted treatment modality nowadays. However, major challenge with the treatment is that, patient recovery is very low. Therefore, combination therapies are being investigated and some of them are at the clinical stage with FDA approval. In this chapter, we will discuss currently available immunotherapy drugs and their synergistic effects in combination with chemotherapy drugs or two different immunotherapy drugs.

Keywords:

Checkpoint blockades Chemotherapy, Combination therapy, Immunotherapy, Monoclonal antibodies, Synergistic, Vaccines.

Affiliation:

Sidra Medical and Research Center, Doha, Qatar.