Pp. 86-121 (36)
Treatment of cancer does not depend on a single drug and the existing
strategies are challenged by the the frequent development of drug resistance properties
of cancer cells. Although chemotherapy drugs are still used as the first line of treatment
modalities for cancer, immunotherapyis also used as a targeted treatment modality
nowadays. However, major challenge with the treatment is that, patient recovery is
very low. Therefore, combination therapies are being investigated and some of them
are at the clinical stage with FDA approval. In this chapter, we will discuss currently
available immunotherapy drugs and their synergistic effects in combination with
chemotherapy drugs or two different immunotherapy drugs.
Checkpoint blockades Chemotherapy, Combination therapy,
Immunotherapy, Monoclonal antibodies, Synergistic, Vaccines.
Sidra Medical and Research Center, Doha, Qatar.