Signal Transduction Molecules and Pathways in Cancer: Implication of the Immune System in Modulating Cancer Development and Progression
Pp. 69-85 (17)
Signal transduction pathways and associated molecules play important role
in maintaining cell death and cell survival. However, in cancer cells, some of these
molecules are mutated and lead to cancer progression. These molecules also interfere
with the components of the humoral and the cell mediated immune systems in tumor
environment. Therefore, identifying these can be potential targets for cancer treatment.
Apoptosis, Autophagy, JAK-STAT, K-ras, Myc, p53, Signal
Sidra Medical and Research Center, Doha, Qatar.