Isoindole derivatives constitute an important class of biologically active heterocyclic compounds
and continue to attract considerable attention due to their diverse pharmacological profile
such as, antimicrobial, anthelmintic, insecticidal, cyclooxygenase isoenzyme (COX-2) and thrombin
inhibition with special emphasis on anticancer activity. This review highlights anticancer properties
of isoindole derivatives and its related structures and hoping that it would further help in generation
of new concepts towards rational design and development of more potent and less toxic anticancer
Keywords: Anti-cancer agents, Isoindole, Isoindoline, Isoindolinone, Phthalimide, Chemotherapy.
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