Abstract
Background: Stevioside is one of the most important food additives that has become well known for its sweetness. The aim of this study was to evaluate the impact of Stevioside on the heart.
Methods: 4-day-old embryonated chickens eggs were inoculated with Stevioside and kept until hatching. Shortly after, the heart tissue samples were taken to examine organ Oxidative stresses by measuring Malondialdehyde (MDA) and glutathione (GSH) levels, ferric reducing /antioxidant power (FRAP) and cupric ion reducing assay (CUPRIC).
Results: There was no significant difference in glutathione level, lipid peroxidation, FRAP, and cupric assay.
Conclusion: It was suggested that stevioside did not cause marked damages to heart tissues in chicken embryo model.
Keywords: Glycosides, heart effect, oxidative stress, stevioside.
Cardiovascular & Hematological Disorders-Drug Targets
Title:The Effect of Stevia on the Chicken Embryo Heart
Volume: 16 Issue: 1
Author(s): Parisa Sadighara, Isa Mohammadpour, Mahdi Jahanbakhsh, Atefeh Araghi and Ahmad Nazaktabar
Affiliation:
Keywords: Glycosides, heart effect, oxidative stress, stevioside.
Abstract: Background: Stevioside is one of the most important food additives that has become well known for its sweetness. The aim of this study was to evaluate the impact of Stevioside on the heart.
Methods: 4-day-old embryonated chickens eggs were inoculated with Stevioside and kept until hatching. Shortly after, the heart tissue samples were taken to examine organ Oxidative stresses by measuring Malondialdehyde (MDA) and glutathione (GSH) levels, ferric reducing /antioxidant power (FRAP) and cupric ion reducing assay (CUPRIC).
Results: There was no significant difference in glutathione level, lipid peroxidation, FRAP, and cupric assay.
Conclusion: It was suggested that stevioside did not cause marked damages to heart tissues in chicken embryo model.
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Cite this article as:
Sadighara Parisa, Mohammadpour Isa, Jahanbakhsh Mahdi, Araghi Atefeh and Nazaktabar Ahmad, The Effect of Stevia on the Chicken Embryo Heart, Cardiovascular & Hematological Disorders-Drug Targets 2016; 16 (1) . https://dx.doi.org/10.2174/1871529X16666160527140939
DOI https://dx.doi.org/10.2174/1871529X16666160527140939 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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