Development of Arene Ruthenium Antitumor Complexes

Author(s): Wei Su, Zhaofeng Tang, Peiyuan Li

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 16 , Issue 10 , 2016

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Abstract:

The organometallic arene ruthenium complexes are rapidly advancing. In particular, the organoruthenium complexes of the type [(η6-arene)Ru(X)(Y)(Z)] have attracted increasing attention for their special structures and properties. This review is focused on the recent developments of [(η6- arene)Ru(X)(Y)(Z)]-typed complexes incorporating various biologically active ligands, which are important in the exploration of novel multi-targeted organometallic anticancer drugs.

Keywords: Anticancer agent, Arene, Biologically active ligands, Ruthenium.

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Article Details

VOLUME: 16
ISSUE: 10
Year: 2016
Page: [787 - 795]
Pages: 9
DOI: 10.2174/138955751610160503003937
Price: $65

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