Neurotrophic and Neuroprotective Effects of Muscle Contraction

Author(s): Valentina Arnao, Domenico Di Raimondo, Antonino Tuttolomondo, Antonio Pinto

Journal Name: Current Pharmaceutical Design

Volume 22 , Issue 24 , 2016

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Background: Physical activity has been shown to be associated with reduced risk of coronary heart disease but the same effect seems to be produced in neurological diseases. Objective: In this review, we focused on the interplay between physical activity and some neurological conditions (Stroke, dementia, epilepsy, headache, Parkinson’ s disease, amyotrophic lateral sclerosis, multiple sclerosis, insomnia, depression and anxiety) with the aim of describing the potential role of physical activity in the prevention of such diseases and the physiological mechanisms involved in these processes. Results: Despite a growing body of evidence which reveals that physical activity is able to reduce the frequency of neurological diseases, directly or indirectly by enhancing cardiovascular conditions, further studies are necessary to better characterize which type of exercise is useful for each condition. Conclusion: Physical activity could represent an additional approach to fight against such diseases.

Keywords: Physical activity, neurological disease, lifestyle, prevention, rehabilitation.

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Article Details

Year: 2016
Page: [3749 - 3763]
Pages: 15
DOI: 10.2174/1381612822666160428111234
Price: $65

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