Background: Chiral insecticides significantly contribute to the environmental
pollutions recently. As the development of industry and agriculture, increasing number
of chiral insecticides are to be introduced into the market. However, their enantioselective
toxicology to ecosystem still remains uncertain.
Methods: In this review, we embarked on a structured search of bibliographic databases
for peer-reviewed articles regarding the enantioselective effects of bifenthrin, a typical
chiral insecticide, on both target and non-target species.
Results: With this enantioselective property of chiral insecticides, they often exhibit adverse
effects on non-target species enantioselectively. Specifically, the enantioselective
effects of bifenthrin on target and non-target organisms were discussed. In target species, R-bifenthrin exerts
more significant activities in deinsectization, compared with S-bifenthrin. On the other hand, Sbifenthrin
is more toxic to non-target species than R-bifenthrin, which suggests that the application of sole
enantiomer is more efficient and environment-friendly than that of racemate.
Conclusion: This review confirms the choice of environment-friendly insecticides from the perspective of
the enantioselectivity of chiral insecticides. To make insecticides more efficient to target species and less
toxic to non-target species, further research should be done to investigated the potential effects of targetactive
enantiomers on non-target organisms as well as the enantioselective fate of enantiomers in multiple