Title:Therapeutical Perspectives of S-Allylcysteine: Effect on diabetes and other disorders in Animal Models
VOLUME: 15 ISSUE: 2
Author(s):V.V. Sathibabu Uddandrao, Parim Brahmanaidu and G. Saravanan*
Affiliation:Department of Biochemistry, K.S. Rangasamy College of Arts and Science, Tiruchengode - 637215, Tamil Nadu, Department of Biochemistry, S.V. University, Tirupati, Andhra Pradesh, Department of Biochemistry, K.S. Rangasamy College of Arts and Science, Tiruchengode - 637215, Tamil Nadu
Keywords:S-Allylcysteine, diabetes mellitus, antioxidants, metabolic disorders, natural medicines, garlic components.
Abstract:Background: Plants derived constituents with impending therapeutic values have been used long
time to cure various diseases and disorders including Diabetes Mellitus (DM). Various restorative herbs have
become portion of food as vegetables, spice, and organic products. In current days, there is mounting facts that
natural foods molecules, because of their natural possessions, are perhaps inimitable nutraceuticals, possessing
additional remedies for diverse characteristics of Diabetes. In present appraise, addressed the latent potentiality
of a sulfur containing amino acid S-Allylcysteine (SAC), which was derived from garlic on Diabetes mellitus
and other disorders. Substantiating with a number of in vitro, animal experiments and some human clinical
trails, SAC revise glucose and lipid metabolism, amend hyperglycemia, insulin resistance, and hyperlipidemia,
convalesce metabolism of adipose tissue, and oxidative stress development and pathways of stress-sensitive
signaling and inflammatory associated issues.
Conclusion: S-Allycysteine showed several beneficial effects on various disorders and there is no scientific
evidence against S-Allycysteine adverse effects, and proved that consumption of S-Allylcysteine
has numerous pharmacological benefits.
