Onychomycosis (fungal nail infections) is very common worldwide but is fortunately not often lethal.
Several powerful drugs have been introduced into clinical practice in recent years, but these infections
remain difficult to cure primarily due to the difficulty of penetration of drug to the site of the infection in
therapeutic concentrations. The nature of the disease, the causative fungi, and the characteristics of the drugs
employed to treat this condition are discussed in this review.
Keywords: Antifungal drugs, onychomycosis, dermatophytes, griseofulvin, azoles, polyene macrolides, allyl
amines, ciclopirox, tavaborole, tea tree oil.
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