Marine environment exhibits an enormous diversity of organisms which contains an abundant source of
polysaccharides. As polymer matrix carriers, marine-based polymers possess several valuable properties including
high stability, non-toxicity, hydrophilicity, biodegradability, with low production cost. Despite notable biological
activities of these natural polymers, there are certain limitations in exploring their functions in applications of
nano-sized drug delivery systems. The review aims to demonstrate exceptional characteristics of marine-based
polymers including fucoidan, alginate, carrageenan, hyaluronic acid, chondroitin sulfate, and chitosan as well as
provide perspectives of current publications on their nanoparticle formulations for biomedical applications.