Conventional and New Antiepileptic Drugs on Vitamin D and Bone Health: What We Know to Date?

Author(s): Antonio Siniscalchi, Giovambattista De Sarro, Andzelika Michniewicz, Luca Gallelli

Journal Name: Current Clinical Pharmacology

Volume 11 , Issue 1 , 2016

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The treatment with antiepileptic drugs (AEDs), in particular conventional drugs, induces an increased risk of fractures in women and in epileptic patients in treatment with AEDs for more than 12 years. A supplementation with calcium and vitamin D is suggested in patients chronically treated with some AEDs and there are recommendations to do so. The lack of significant conclusive evidence about the effects of conventional and newer AEDs on bone metabolism needs for more clinical studies in order to perform an appropriate use of calcium and vitamin D supplementation in young and ederly epileptic patients.

Keywords: AEDs, bone metabolism, calcium, vitamin D, women.

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Article Details

Year: 2016
Page: [69 - 70]
Pages: 2
DOI: 10.2174/157488471101160204121835

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PDF: 61