Background: Cosmetic and reconstructive surgery relies extensively on the complex relationship
between skin, soft tissue and the underlying bone skeleton. Soft tissue loss and acquired soft tissue deficits are
some of the daily challenges faced by the plastic surgeon. Fat grafting has become one of the standard lines of
care that has various applications in plastic surgery treatments. The ability of adipose stem cells to rejuvenate
tissues is promising for plastic surgery. Bone disorders, including infection and poor healing, pose vexing
problems to the reconstructive surgeon. Vascular surgery is a technique necessary for the reconstruction of the
most challenging surgical defects, and has great potential for improvement through technology.
Methods: We performed a structured search of all recent United States Patents with reference to plastic and
reconstructive surgery. Two investigators then reviewed all patents with specific applications to plastic and
reconstructive surgery, and regenerative medicine.
Results: Eight specific patents were included for review in this article.
Conclusion: Recent patents discussed in this article demonstrate promise to dramatically improve a number of
specific patient conditions. Nanoscale refinements of current techniques may offer more efficient and
improved surgical and non-surgical approaches for reconstruction. Such refinements will significantly expand
our capabilities for innovative reconstructive interventions, with high efficiency, specificity and minimal