Title:RBM15 Functions in Blood Diseases
VOLUME: 16 ISSUE: 7
Author(s):Mengyu Hu, Yuxia Yang, Zhi Ji and Jianyuan Luo
Affiliation:Department of Medical Genetics, Peking University Health Science Center, Beijing, China, 100191., Department of Medical & Research Technology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Keywords:RBM15, blood diseases, function, mechanism.
Abstract:RBM15, an RNA-binding protein, plays important roles in the growth
and apoptosis of cells, especially blood cells through regulating multiple signal
pathways such as Notch and Wnt. An increasing body of evidence has suggested
that RBM15 may play a key function on the development of various blood diseases, such as
acute/chronic myeloid leukemia and kaposi′s sarcoma. In this review, we will focus on the progress
of the association between RBM15 and its related blood diseases.
