Comprehensive Practical Hepatology

Acute and chronic liver disease is a global endemic healthcare concern. More than 500 million people around the world are infected with the hepatitis B or C virus. Approximately 500,000 patients die ...
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Approach to Children with Abnormal Liver Function Tests Results

Pp. 199-213 (15)

Masami Minemura


Although the incidence of acquired liver diseases such as viral hepatitis or fatty liver is lower during infancy and childhood than in adults, congenital or metabolic disorders should be suspected in children with liver dysfunction. It should be noted that normal ranges of biochemical liver tests in children are different from those of adult subjects. Pediatric liver diseases may cause a life threatening event, such as kernicterus, intracranial hemorrhage, or metabolic derangements.


Children, congenital disease, fatty liver, liver dysfunction, metabolic disease, viral hepatitis.


The Third Department of Internal Medicine, University of Toyama, Toyama, Japan.