Comprehensive Practical Hepatology

Acute and chronic liver disease is a global endemic healthcare concern. More than 500 million people around the world are infected with the hepatitis B or C virus. Approximately 500,000 patients die ...
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Approach to Patients with Acute Liver Injury

Pp. 49-76 (28)

Yasuhiro Nakayama and Yukihiro Shimizu


Although acute liver injury shows spontaneous improvement in many patients, some require special treatment and can develop fulminant hepatic failure. The etiology of acute hepatitis and acute hepatic failure varies in different countries, making prompt diagnosis and determination of etiology important for determining prognosis and proper patient management. Liver transplantation should be considered for patients who develop fulminant hepatic failure.


Acute liver failure, acute liver injury, cholestatic type, hepatocellular type, liver transplantation, medical history, physical findings, signs, symptoms, viral hepatitis.


The First Department of Internal Medicine, University of Yamanashi, Yamanashi, Japan.