Title:Biomimetic Approaches Towards The Synthesis of Complex Dimeric Natural Products
VOLUME: 22 ISSUE: 12
Author(s):Paul A. Stanley, Christian Spiteri, Jonathan C. Moore, Andrew S. Barrow, Pallavi Sharma and John E. Moses
Affiliation:School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK
Keywords:Biomimetic, dimer, natural product, total synthesis.
Abstract:We present a selection of elegant and diverse biomimetic syntheses of complex natural product dimers.
The dimerisation pathways discussed encompass the most prevalent strategies, including: Diels-Alder, Aldol, Mannich,
conjugate addition, oxidative, radical and photochemical approaches; each underpinned through rational biosynthetic
speculation.