Temporomandibular disorders (TMD) have been discussed for more than 70 years without
reaching consensus on causes, etiological factors, pathophysiology, or rationale management. Indeed,
TMD pain remains an enigma and a diagnostic and management challenge for many clinicians. Perhaps the many and often
conflicting views on TMD pain by different health care providers are routed in professional traditions, personal beliefs,
experience, and clinical training. This review aims to provide an updated and critical discussion on what is known
and supported by scientific evidence about myofascial TMD pain and which gaps there still may be in our understanding
of this condition. It has not been the intention to make a systematic review on all aspects of TMD but rather to point out
some of the more recent (and important) pieces of information that may help us to better appreciate TMD pain as a complex
and multifaceted pain disorder manifested in the craniofacial system.
Keywords: Temporomandibular pain, sensitization, treatment, patient-centered management.
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