Abstract
The development of novel T cell therapies to target leukemia has facilitated the translation of this approach for hematologic malignancies. Different methods of manufacturing leukemia-specific T cells have evolved, along with additional measures to increase the safety of this therapy. This is an overview of expanded T cell therapeutics with a focus on how the manufacturing strategies have been refined, and where the research is heading.
Keywords: Cell therapy, leukemia antigens, ex vivo expanded T cells.
Current Drug Targets
Title:Adoptive Immunotherapy For Leukemia With Ex vivo Expanded T Cells
Volume: 18 Issue: 3
Author(s): Conrad R.Y. Cruz and Catherine M. Bollard
Affiliation:
Keywords: Cell therapy, leukemia antigens, ex vivo expanded T cells.
Abstract: The development of novel T cell therapies to target leukemia has facilitated the translation of this approach for hematologic malignancies. Different methods of manufacturing leukemia-specific T cells have evolved, along with additional measures to increase the safety of this therapy. This is an overview of expanded T cell therapeutics with a focus on how the manufacturing strategies have been refined, and where the research is heading.
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Cite this article as:
Cruz R.Y. Conrad and Bollard M. Catherine, Adoptive Immunotherapy For Leukemia With Ex vivo Expanded T Cells, Current Drug Targets 2017; 18 (3) . https://dx.doi.org/10.2174/1389450117666160209143529
DOI https://dx.doi.org/10.2174/1389450117666160209143529 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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