Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are
scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective
improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and
botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential
drug treatment for FOG in Parkinsonism.
Keywords: Drug treatment, freezing of gait, Levodopa, Parkinson’s disease, Parkinsonism.
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