Wilson’s disease (WD), also called hepatolenticular degeneration, is an
autosomal recessive inheritance disorder of copper metabolism characterized by the
multiple mutations in the ATP-ase 7B gene of chromosome 13q. About half of the
WD patients have neurological or psychiatric symptoms. As WD is a kind of
medicable or nearly curable neurodegenerative disease in the field of medicine, early
consideration/examination and without delay/ life-long treatment usually lead to better prognoses. The drugs, also named
as anticopper agents, are commonly used in clinics including D-penicillamine, trientine, sodium dimercaptosuccinate,
dimercaptosuccinic acid, zinc and tetrathiomolybdate. This provides detailed reviews about these medicines.