Abstract
Nitric Oxide (NO) is a molecule of extreme interest to biologists, pharmacologists, physiologists, and biochemists, characterized as a mediator in the cardiovascular system. It has been found to be implicated in various pathological processes. NO is synthesized enzymatically by Nitric Oxide Synthases (NOSs) from L-arginine, and therefore NOSs have emerged as very crucial therapeutic targets. Herein, a series of extracts from plants as well as a number of isolated compounds acting as NOS inhibitors are presented.
Keywords: Nitric oxide synthase inhibitors, naturally occurring NOS inhibitors, NOS inhibitors from plants, isolated natural compounds, extracts from plants.
Current Enzyme Inhibition
Title:Nitric Oxide Synthases and Their Natural Inhibitors
Volume: 12 Issue: 1
Author(s): Christos Kontogiorgis and Dimitra Hadjipavlou-Litina
Affiliation:
Keywords: Nitric oxide synthase inhibitors, naturally occurring NOS inhibitors, NOS inhibitors from plants, isolated natural compounds, extracts from plants.
Abstract: Nitric Oxide (NO) is a molecule of extreme interest to biologists, pharmacologists, physiologists, and biochemists, characterized as a mediator in the cardiovascular system. It has been found to be implicated in various pathological processes. NO is synthesized enzymatically by Nitric Oxide Synthases (NOSs) from L-arginine, and therefore NOSs have emerged as very crucial therapeutic targets. Herein, a series of extracts from plants as well as a number of isolated compounds acting as NOS inhibitors are presented.
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Cite this article as:
Kontogiorgis Christos and Hadjipavlou-Litina Dimitra, Nitric Oxide Synthases and Their Natural Inhibitors, Current Enzyme Inhibition 2016; 12 (1) . https://dx.doi.org/10.2174/1573408012666151126185628
DOI https://dx.doi.org/10.2174/1573408012666151126185628 |
Print ISSN 1573-4080 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6662 |
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