Abstract
Nano-liposomes are the newly developed delivery systems for cancer therapy that are finding a position particularly suitable as peptide and protein carriers. These are three-layered self-assembled structures with nanoparticulate carrier systems. The overall pharmacological properties of commonly used protein and peptide in cancer therapy can be improved by the incorporation of protein and peptide into the nano-liposome. The surface modifications can be made liposomes to make compatible with targeting ligands has made these nanocarriers for targeted delivery. This review discusses the method of preparation and characterization of liposome based protein peptide delivery for the treatment of cancer. This review also explores latest work intended for targeted treatment of cancer by nano-liposomal protein and peptide delivery system. This type of delivery is targeting protein and peptide to tumor site by avoiding the reticuloendothelial system. Methods of nano-liposome delivery containing protein and peptide are also highlighted.
Keywords: Nanotechnology, protein, peptide, nanoliposome, targeting, cancer, parenteral delivery.
Anti-Cancer Agents in Medicinal Chemistry
Title:Nanoliposome is a Promising Carrier of Protein and Peptide Biomolecule for the Treatment of Cancer
Volume: 16 Issue: 7
Author(s): Tapan Kumar Giri, Ayan Giri, Tapan Kumar Barman and Subhasis Maity
Affiliation:
Keywords: Nanotechnology, protein, peptide, nanoliposome, targeting, cancer, parenteral delivery.
Abstract: Nano-liposomes are the newly developed delivery systems for cancer therapy that are finding a position particularly suitable as peptide and protein carriers. These are three-layered self-assembled structures with nanoparticulate carrier systems. The overall pharmacological properties of commonly used protein and peptide in cancer therapy can be improved by the incorporation of protein and peptide into the nano-liposome. The surface modifications can be made liposomes to make compatible with targeting ligands has made these nanocarriers for targeted delivery. This review discusses the method of preparation and characterization of liposome based protein peptide delivery for the treatment of cancer. This review also explores latest work intended for targeted treatment of cancer by nano-liposomal protein and peptide delivery system. This type of delivery is targeting protein and peptide to tumor site by avoiding the reticuloendothelial system. Methods of nano-liposome delivery containing protein and peptide are also highlighted.
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Cite this article as:
Kumar Giri Tapan, Giri Ayan, Kumar Barman Tapan and Maity Subhasis, Nanoliposome is a Promising Carrier of Protein and Peptide Biomolecule for the Treatment of Cancer, Anti-Cancer Agents in Medicinal Chemistry 2016; 16 (7) . https://dx.doi.org/10.2174/1871520616666151116121821
DOI https://dx.doi.org/10.2174/1871520616666151116121821 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
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