Background: Investigation on and the utilization of polyphenols, acquire presently attracted major fascination
about the functional foods, nutraceutical and pharmaceutical industries, owing to their prospective
health advantages to mankind.
Limitation of Polyphenols: Nevertheless, the utilization of polyphenols appears to be limited because
of their low aqueous solubility, minimal oral bioavailability and short biological half life. These issues
limit the bioaccessibility and potential health benefits of this polyphenol in pharmaceutical products.
Conclusion: Recently, various encapsulation technologies are designed for enhancing the solubility, bioavailability and
controlled release of polyphenols. In this review, we have discussed various formulation strategies used for the polyphenols
to overcome the drawbacks associated with poor stability and bioavailability.