Abstract
Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.
Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.
Current Stem Cell Research & Therapy
Title:The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy
Volume: 11 Issue: 8
Author(s): Greg Lemon, Sebastian Sjoqvist, Mei Ling Lim, Neus Feliu, Alexandra B. Firsova, Risul Amin, Ylva Gustafsson, Annika Stuewer, Elena Gubareva, Johannes Haag, Philipp Jungebluth and Paolo Macchiarini
Affiliation:
Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.
Abstract: Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.
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Lemon Greg, Sjoqvist Sebastian, Lim Ling Mei, Feliu Neus, Firsova B. Alexandra, Amin Risul, Gustafsson Ylva, Stuewer Annika, Gubareva Elena, Haag Johannes, Jungebluth Philipp and Macchiarini Paolo, The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy, Current Stem Cell Research & Therapy 2016; 11 (8) . https://dx.doi.org/10.2174/1574888X10666151001115942
DOI https://dx.doi.org/10.2174/1574888X10666151001115942 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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