Abstract
Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.
Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.
Current Stem Cell Research & Therapy
Title:The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy
Volume: 11 Issue: 8
Author(s): Greg Lemon, Sebastian Sjoqvist, Mei Ling Lim, Neus Feliu, Alexandra B. Firsova, Risul Amin, Ylva Gustafsson, Annika Stuewer, Elena Gubareva, Johannes Haag, Philipp Jungebluth and Paolo Macchiarini
Affiliation:
Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.
Abstract: Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.
Export Options
About this article
Cite this article as:
Lemon Greg, Sjoqvist Sebastian, Lim Ling Mei, Feliu Neus, Firsova B. Alexandra, Amin Risul, Gustafsson Ylva, Stuewer Annika, Gubareva Elena, Haag Johannes, Jungebluth Philipp and Macchiarini Paolo, The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy, Current Stem Cell Research & Therapy 2016; 11 (8) . https://dx.doi.org/10.2174/1574888X10666151001115942
DOI https://dx.doi.org/10.2174/1574888X10666151001115942 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Targets for Medical Therapy to Limit Abdominal Aortic Aneurysm Progression
Current Drug Targets Protein Tyrosine Nitration: Role in Aging
Current Aging Science [11C]Meta-Hydroxyephedrine PET/CT
Current Radiopharmaceuticals Pathogenesis-Oriented Targets for Adjunctive Therapy
Endocrine, Metabolic & Immune Disorders - Drug Targets Inhibitory Effect on Replicative DNA Polymerases, Human Cancer Cell Proliferation, and In Vivo Anti-Tumor Activity by Glycolipids from Spinach
Current Medicinal Chemistry Oxidative Stress, Inflammation and Endothelial Biomarkers in Arterial Hypertension
Current Hypertension Reviews Central Nervous System Circuitry and Peripheral Neural Sympathetic Activity Responsible for Essential Hypertension
Current Neurovascular Research An Indirect Screen for Brain Uptake of 1,2-Diarylethane Melanocortin 4 Receptor Antagonists in Rats
Drug Metabolism Letters Novel Systemic Drugs for Cutaneous T-Cell Lymphoma
Recent Patents on Anti-Cancer Drug Discovery High-Density Lipoprotein at the Interface of Type 2 Diabetes Mellitus And Cardiovascular Disorders
Current Pharmaceutical Design Indications for Heart Transplantation in Congenital Heart Disease
Current Cardiology Reviews Genetic Basis of Renal Mass in Rat Models
Current Hypertension Reviews Inflammatory Mediators and the Failing Heart: A Translational Approach
Current Molecular Medicine The Effect of Resveratrol dose and Duration of Treatment on Blood Pressure in Patients with Cardiovascular Disorders: A Systematic Review
Current Drug Discovery Technologies Redox State in Atrial Fibrillation Pathogenesis and Relevant Therapeutic Approaches
Current Medicinal Chemistry Incidence and Prevalence of Hypothyroidism in Patients Affected by Chronic Heart Failure: Role of Amiodarone
Endocrine, Metabolic & Immune Disorders - Drug Targets Critical Determinants of Cardiovascular Risk in Rheumatoid Arthritis
Current Pharmaceutical Design Oxidative Stress and Pathophysiology of Ischemic Stroke: Novel Therapeutic Opportunities
CNS & Neurological Disorders - Drug Targets Targeting the Secretory Pathway for Anti-Inflammatory Drug Development
Current Topics in Medicinal Chemistry The Potential of Flavonolignans in Prostate Cancer Management
Current Medicinal Chemistry