Polysaccharides are natural polymers, obtained from a large variety of sources ranging from
fungi to more complex organisms such as birds and whales. Their use for pharmaceutical and biomedical
applications has been the subject of numerous researches by the world´s academia. Polysaccharide
chemical/physical modifications leading to graft copolymers are discussed in this review, focusing
on those nanosystems that are potential candidates for drug delivery applications. Therefore,
this review focuses on the biomedical application of polysaccharide based copolymers, particularly as
nanocarriers. Copolymer of polysaccharides such as alginate, cellulose, chitosan, dextran, guar, hyaluronic acid, pullulan
and starch as drug delivery nanocarriers will be discussed.