Abstract
This review presents most of the literature data about synthesis and biological activity of pyrazolo[4,3-c]heterocyclic derivatives. Pyrazolo[4,3-c]heterocyclic derivatives show the antimicrobial, anti-inflammatory, antiviral, antitumor, analgesic and antiphlogistic activities, and effects on the nervous and immune system. The broad spectrum of biological activity of pyrazolo[4,3-c]heterocyclic derivatives is the main reason for the preparation of new compounds containing this scaffold.
Keywords: Biological activity, pyrazolo[4, 3-c]heterocyclic derivatives; pyrazolo[4, 3-c]pyridines, pyrazolo[4, 3-c]quinolones; synthesis.
Mini-Reviews in Organic Chemistry
Title:Synthesis and Biological Activity of Pyrazolo[4,3-c]heterocyclic Derivatives: A Mini Review
Volume: 12 Issue: 4
Author(s): Anna Wojcicka and Lilianna Becan
Affiliation:
Keywords: Biological activity, pyrazolo[4, 3-c]heterocyclic derivatives; pyrazolo[4, 3-c]pyridines, pyrazolo[4, 3-c]quinolones; synthesis.
Abstract: This review presents most of the literature data about synthesis and biological activity of pyrazolo[4,3-c]heterocyclic derivatives. Pyrazolo[4,3-c]heterocyclic derivatives show the antimicrobial, anti-inflammatory, antiviral, antitumor, analgesic and antiphlogistic activities, and effects on the nervous and immune system. The broad spectrum of biological activity of pyrazolo[4,3-c]heterocyclic derivatives is the main reason for the preparation of new compounds containing this scaffold.
Export Options
About this article
Cite this article as:
Wojcicka Anna and Becan Lilianna, Synthesis and Biological Activity of Pyrazolo[4,3-c]heterocyclic Derivatives: A Mini Review, Mini-Reviews in Organic Chemistry 2015; 12 (4) . https://dx.doi.org/10.2174/1570193X12666150930224649
DOI https://dx.doi.org/10.2174/1570193X12666150930224649 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
Call for Papers in Thematic Issues
Navigating the 2D Universe in Organic Chemistry
This special issue explores the transformative impact of two-dimensional (2D) materials on the realm of organic chemistry, unraveling new possibilities for synthesis, functionalization, and applications of organic compounds. Focused on the unique chemistry within this novel dimension, the issue highlights breakthroughs in the field of 2D organic chemistry. Contributions are ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Update of NGAL in Acute Kidney Injury
Current Protein & Peptide Science Systemic Delivery of Curcumin: 21st Century Solutions for an Ancient Conundrum
Current Drug Discovery Technologies Genome and Transcriptome Analysis of Neuroblastoma Advanced Diagnosis from Innovative Therapies
Current Pharmaceutical Design Restoring TRAIL Induced Apoptosis Using Naturopathy. Hercules Joins Hand with Nature to Triumph Over Lernaean Hydra
Current Genomics Application of Solvent Influenced Fluorescence-quenching and Enhancement to Develop a Highly Sensitive HPLC Methodology for Analysis of Resveratrol-PEG Conjugates
Current Pharmaceutical Analysis The Development of a Rapid, Simple and Sensitive LC-MS/MS Method, to Guide Clinical Dosing, for the Analysis of 5-Fluorouracil in Human Plasma
Current Pharmaceutical Analysis Lessons to Learn from Crohn's Disease Clinical Trials: Implications for Ulcerative Colitis
Current Drug Targets Tuftsin – Properties and Analogs
Current Medicinal Chemistry Using Insights into Pim1 Structure to Design New Anticancer Drugs
Current Pharmaceutical Design Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease
Current Medicinal Chemistry Interaction of Macrocyclic Lactones with the Multidrug Transporters: The Bases of the Pharmacokinetics of Lipid-Like Drugs
Current Drug Metabolism The Economics of Pharmacogenomics
Current Pharmacogenomics Assays for Identification of Hsp90 Inhibitors and Biochemical Methods for Discriminating their Mechanism of Action
Current Topics in Medicinal Chemistry Safety and Efficacy Assessment of a Sanitary Pad Containing Potassium Alum in Comparison to Ordinary Pads: A Cross-Over Trial
Current Women`s Health Reviews Oxidative Stress, Redox Signaling and Cancer Chemoresistance: Putting Together the Pieces of the Puzzle
Current Medicinal Chemistry Human Multidrug Transporter ABCG2, a Target for Sensitizing Drug Resistance in Cancer Chemotherapy
Current Medicinal Chemistry Mevalonate Kinase Deficiency: Disclosing the Role of Mevalonate Pathway Modulation in Inflammation
Current Pharmaceutical Design Phytoestrogens and other Botanicals: On the Problems of Evidence-based Evaluation
Recent Patents on Cardiovascular Drug Discovery Modulation of Sensitivity to Antitumor Agents by Targeting the MAPK Survival Pathway
Current Pharmaceutical Design Curcumin Modulates Glycolytic Metabolism and Inflammatory Cytokines via Nrf 2 in Dalton’s Lymphoma Ascites Cells In Vivo
Anti-Cancer Agents in Medicinal Chemistry