Title:Synthesis and Biological Activity of Pyrazolo[4,3-c]heterocyclic Derivatives: A Mini Review
VOLUME: 12 ISSUE: 4
Author(s):Anna Wojcicka and Lilianna Becan
Affiliation:Department of Drugs Technology, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Keywords:Biological activity, pyrazolo[4, 3-c]heterocyclic derivatives; pyrazolo[4, 3-c]pyridines,
pyrazolo[4, 3-c]quinolones; synthesis.
Abstract:This review presents most of the literature data about synthesis and biological activity of
pyrazolo[4,3-c]heterocyclic derivatives. Pyrazolo[4,3-c]heterocyclic derivatives show the antimicrobial,
anti-inflammatory, antiviral, antitumor, analgesic and antiphlogistic activities, and effects on the
nervous and immune system. The broad spectrum of biological activity of pyrazolo[4,3-c]heterocyclic
derivatives is the main reason for the preparation of new compounds containing this scaffold.