Benzoxazepine is a bi-cyclic heterocyclic compound of a benzene ring fused to an oxazepine
ring. Various benzoxazepine derivatives have been synthesized and evaluated for various biological
activities. Some analogs derivatives have shown potent biological activities and may be considered
as lead molecule for the development of future drugs. This review highlights the different biological
activities like anticonvulsant, antimicrobial, anticancer, antipsychotic agents, calcium antagonists
and neuroprotective. Since no comprehensive review on biological potential of benxozapine is
available, this review covers all the literature reports with patents by giving emphasis on synthetic
schemes and biological activities of the different benzoxazepine analogs.