Clinical Assessment of Cognitive Decline in Adults with Down Syndrome

Author(s): Marwan Sabbagh, Jamie Edgin

Journal Name: Current Alzheimer Research

Volume 13 , Issue 1 , 2016

  Journal Home
Translate in Chinese
Become EABM
Become Reviewer
Call for Editor


Down syndrome is an intellectual disability requiring periodic monitoring of cognition given the near universal presence of Alzheimer’s Disease related neuropathology and high rates of dementia in middle adulthood. We review current approaches to detecting decline in this population, including informant-based measures, dementia screening tools, and neuroimaging techniques. The challenges for detecting decline in this group are discussed, including the need to take into account premorbid cognitive function as well as medical comorbidity.

Keywords: Alzheimer’s disease, assessment, decline, dementia, down syndrome, neuropsychological, sleep.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2016
Published on: 20 September, 2015
Page: [30 - 34]
Pages: 5
DOI: 10.2174/1567205012666150921095724

Article Metrics

PDF: 83
HTML: 18
PRC: 1