Alterations in Hepatic Lipid Metabolism, and their Relation to Dietary Macronutrients in Pediatric Nonalcoholic Fatty Liver Disease

Author(s): David E. St-Jules, Corilee A. Watters

Journal Name: Drug Metabolism Letters

Volume 9 , Issue 2 , 2015

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Nonacoholic fatty liver disease (NAFLD) is a common complication of pediatric obesity in which diet is a major factor in causation and the cornerstone of treatment. In this review, the alterations in hepatic lipid metabolism that contribute to pediatric NAFLD, and impact of dietary proteins, carbohydrates, and fats on hepatic fat metabolism and NAFLD are described. Lastly, dietary recommendations for achieving changes in macronutrient intakes that can be beneficial in the treatment of NAFLD are provided.

Keywords: Adolescents, children, diet, lipid, macronutrient, nutrition, nonalcoholic fatty liver disease, pediatric.

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Article Details

Year: 2015
Page: [72 - 79]
Pages: 8
DOI: 10.2174/1872312809666150907115208
Price: $65

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PDF: 40