Drug Likeness and Selective Functionalization of Quinoxalines

Author(s): Samuel R. A. Ferreira, Marcia S. F. Franco, Evelyn M. L. P. Diniz, Flavio da Silva Emery, Giuliano Cesar Clososki

Journal Name: Current Organic Synthesis

Volume 12 , Issue 6 , 2015

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Abstract:

In recent years, the pharmacological potential of quinoxalines has received vast interest due to its many applications. This review centers on a critical overview of chemical diversity and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies for obtaining structurally diverse quinoxalines using highly selective processes will be discussed.

Keywords: Quinoxaline, heterocycles, C-H activation, drug-likeness, organometallics.

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Article Details

VOLUME: 12
ISSUE: 6
Year: 2015
Published on: 28 August, 2015
Page: [714 - 729]
Pages: 16
DOI: 10.2174/157017941206150828110053
Price: $65

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