Title:Drug Likeness and Selective Functionalization of Quinoxalines
VOLUME: 12 ISSUE: 6
Author(s):Samuel R. A. Ferreira, Marcia S. F. Franco, Evelyn M. L. P. Diniz, Flavio da Silva Emery and Giuliano Cesar Clososki
Affiliation:Faculdade de Ciências Farmacêuticas de Ribeirão Preto; Universidade de São Paulo, Av. do Café S/N, Ribeirão Preto – SP 14040-903, Brazil.
Keywords:Quinoxaline, heterocycles, C-H activation, drug-likeness, organometallics.
Abstract:In recent years, the pharmacological potential of quinoxalines has received vast interest
due to its many applications. This review centers on a critical overview of chemical diversity
and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies
for obtaining structurally diverse quinoxalines using highly selective processes will be discussed.
