An Acetylated Triterpene Glycoside and Lignans from Phyllanthus myrtifolius and their Antibacterial Activities

Author(s): Neneng Windayani, Lia D. Juliawaty, Euis H. Hakim, Komar Ruslan, Yana M. Syah

Journal Name: The Natural Products Journal

Volume 5 , Issue 3 , 2015

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Phytochemical investigation on the methanol extract of Phyllanthus myrtifolius leaves led to the isolation of a new oleanan derivative, 3β-(3’,4’-di-O-acetyl-α-L-arabinopyranosyl)-12-oleanen- 28-oic acid (1). The structure of compound 1 was determined mainly by extensive NMR data analysis. Together with this compound, six arylnaphtalene lignans 2–7 were also isolated and identified. The isolated compounds 1–7 were tested for their antibacterial activities against eight pathogenic bacteria, showing that compound 1 exhibited highest activity.

Keywords: Antibacterial, euphorbiaceae, lignans, oleanane, Phyllanthus myrtifolius, triterpene.

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Article Details

Year: 2015
Published on: 16 October, 2015
Page: [152 - 157]
Pages: 6
DOI: 10.2174/2210315505666150827213538

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