An Acetylated Triterpene Glycoside and Lignans from Phyllanthus myrtifolius and their Antibacterial Activities

Title:An Acetylated Triterpene Glycoside and Lignans from Phyllanthus myrtifolius and their Antibacterial Activities

Volume: 5 Issue: 3

Author(s): Neneng Windayani, Lia D. Juliawaty, Euis H. Hakim, Komar Ruslan and Yana M. Syah

Affiliation:

Keywords: Antibacterial, euphorbiaceae, lignans, oleanane, Phyllanthus myrtifolius, triterpene.

Abstract: Phytochemical investigation on the methanol extract of Phyllanthus myrtifolius leaves led to the isolation of a new oleanan derivative, 3β-(3’,4’-di-O-acetyl-α-L-arabinopyranosyl)-12-oleanen- 28-oic acid (1). The structure of compound 1 was determined mainly by extensive NMR data analysis. Together with this compound, six arylnaphtalene lignans 2–7 were also isolated and identified. The isolated compounds 1–7 were tested for their antibacterial activities against eight pathogenic bacteria, showing that compound 1 exhibited highest activity.

Cite this article as:

Windayani Neneng, Juliawaty D. Lia, Hakim H. Euis, Ruslan Komar and Syah M. Yana, An Acetylated Triterpene Glycoside and Lignans from Phyllanthus myrtifolius and their Antibacterial Activities, The Natural Products Journal 2015; 5 (3) . https://dx.doi.org/10.2174/2210315505666150827213538