Anti-Inflammatory and Pro-Resolving Effects of N-3 PUFA in Cancers: Structures and Mechanisms

Author(s): Qi Wang, Minghua Hu, Huibi Xu, Xiangliang Yang

Journal Name: Current Topics in Medicinal Chemistry

Volume 16 , Issue 8 , 2016


Become EABM
Become Reviewer
Call for Editor

Graphical Abstract:


Abstract:

As an important hallmark in cancer progress, inflammation attracts more and more interests in recent years. Lots of evidences support the positive effect of n-3 PUFA in inflammation-associated diseases, the supplement of these fatty acids is thought to be promising in the prevention and treatment of cancers. In this review, we summarize some current knowledge of the mechanisms by which n-3 PUFA are thought to attenuate cancer associated inflammation, and we also introduce the current situation of n-3 PUFA in clinic.

Keywords: Anti-inflammation, Breast cancer, Colorectal cancer, Microenvironment, n-3 PUFA, Specialized pro-resolving mediators.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 16
ISSUE: 8
Year: 2016
Published on: 11 November, 2015
Page: [888 - 894]
Pages: 7
DOI: 10.2174/1568026615666150827101602
Price: $65

Article Metrics

PDF: 51
HTML: 2
EPUB: 1
PRC: 1