Biopolymer-Based Delivery Systems: Challenges and Opportunities

Author(s): Iris J. Joye, D. Julian McClements

Journal Name: Current Topics in Medicinal Chemistry

Volume 16 , Issue 9 , 2016

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Graphical Abstract:


Biopolymer-based nanostructures or microstructures can be fabricated with different compositions, structures, and properties so that colloidal delivery systems can be tailored for specific applications. These structures can be assembled using various approaches, including electrospinning, coacervation, nanoprecipitation, injection, layer-by-layer deposition, and/or gelation. A major application of biopolymer-based particles is to encapsulate, protect, and release active molecules in the agricultural, food, supplements, personal care, and pharmaceutical sectors. The inherent variability and complexity of biopolymers (proteins and polysaccharides) often makes it challenging to produce particles with well-defined physicochemical and functional attributes. In this review, we discuss the properties of biopolymers, common particle fabrication methods, and some of the major challenges and opportunities associated with developing biopolymer-based particles for application as food-grade delivery systems.

Keywords: Proteins, Polysaccharides, Nanoparticles, Microparticles, Fibers, Films, Delivery systems, Controlled release.

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Article Details

Year: 2016
Published on: 25 November, 2015
Page: [1026 - 1039]
Pages: 14
DOI: 10.2174/1568026615666150825143130
Price: $65

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PDF: 51
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