Abstract
Haloarenes are important chemical compounds from academic, biological, and industrial point of view. They can usually be prepared by an electrophilic halogenation of aromatic compounds using the halogen in its elemental form (X2), a reaction formerly described by Couper in 1857. Recently, the interest in new reagents that can accomplish a safe, efficient, and convenient halogenation of arenes has grown enormously. The present review summarizes the utilization of trihaloisocyanuric acids in the electrophilic aromatic halogenations and focuses on their green aspects.
Keywords: Arenes, electrophilic reactions, green chemistry, halogenation, N-halo compounds, trihaloisocyanuric acids.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
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