Exploring the Aldol Reaction in the Synthesis of Bioactive Compounds

Author(s): Marco A.B. Ferreira, Luiz C Dias, Ives A. Leonarczyk, Ellen C. Polo, Emílio C. de Lucca

Journal Name: Current Organic Synthesis

Volume 12 , Issue 5 , 2015


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Abstract:

Carbonyl chemistry, specifically aldol reactions, is one of the most efficient and elegant strategies to build carbon-carbon bonds. In the last 15 years in Brazil, our research group and others have worked on the development and application of stereoselective aldol reactions, with direct application in the asymmetric synthesis of several natural products of biological interest. In this review, we highlight the major Brazilian contributions to this field.

Keywords: Aldol Reactions, Stereoselectivity, total synthesis, natural products.

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Article Details

VOLUME: 12
ISSUE: 5
Year: 2015
Published on: 21 August, 2015
Page: [547 - 564]
Pages: 18
DOI: 10.2174/157017941205150821124901
Price: $65

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