We report on synthesis of 1,2-disubstituted benzimidazoles in pure water using nano-structured pyrophosphate Na2CaP2O7.
Our findings showed that this heterogeneous catalyst exhibited high catalytic activity and high selectivity in the synthesis of 1,2-
disubstituted benzimidazoles from direct cyclocondensation of aromatic aldehydes with substituted benzene-1,2-diamine in pure water.
The salient benefits of this method rely on various factors namely: a simple procedure, mildness of the reaction conditions, short reaction
times, operational simplicity, high chemoselectivity, low cost and recyclability of the catalyst.
Keywords: Green chemistry, heterogeneous catalysis, benzimidazoles, diaminoarene, aldehydes, recyclable catalyst.
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