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Recent Patents on Anti-Infective Drug Discovery

Editor-in-Chief

ISSN (Print): 1574-891X
ISSN (Online): 2212-4071

Optimal antibiotic dosage for chronic kidney disease patient: a pharmacological manual for oral clinicians

Author(s): Ramasamy Chidambaram

Volume 10, Issue 2, 2015

Page: [113 - 123] Pages: 11

DOI: 10.2174/1574891X10666150729123754

Price: $65

Abstract

Chronic kidney disease, (CKD) a gradual and inevitable deterioration in renal function, is the disease with the most associations in dentistry. Dosage adjustment is one amongst the vital elements to be familiar with during their oral care. CKD patients take extended duration to filter out medications, therefore dosage must always be tailored under the supervision of nephrologist. The relished benefits from antibiotic could transform as anti-microbial resistance on their abuse and nephrotoxic when contraindicated drugs are encouraged. New patented drug belonging to oxazoliodine group has driven the researchers to handle the emerging AMR. The present communication discusses the pharmacological factors influencing in prescribing the antibiotics for CKD patient from the dentist’s point of view. The formulas destined for calculating the optimal dosage of antibiotics have been documented to aid oral physicians.

Keywords: Antibiotics, chronic kidney disease, dentist, dosage adjustment, glomerular filtration rate, nephrologist.

Graphical Abstract

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