Hydrazones are a versatile linker of connecting various classes of organic compounds with a
unique structural feature of hydrogen bonding donor and the hydrogen bonding acceptor region. An extensive
number of research has been carried out on hydrazone derivatives as a potent class of antitubercular agents.
The present review focuses on the chemistry, antitubercular activity and structure activity relationship (SAR)
of diverse classes of phenyl and heterocyclic based hydrazones.
Keywords: Alamar blue assay, nucleophilic addition, tuberculosis.
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