The first part of the review brings forth the detailed synthesis of the known camphor-derived organocatalysts.
Most synthetic steps are operationally simple, enabling the preparation of the corresponding catalysts on
a larger scale. Frequently, the bicyclic framework of camphor is connected with a proline-derivative through a suitable
spacer, which enables the preparation of a library of organocatalysts needed for the fine-tuning of a selected
stereoselective transformation. The second part of the review focuses on the application of camphor-derived organocatalysts
in various fields of asymmetric organocatalysis. Catalytic reactions are often conducted under mild
reaction conditions giving the corresponding products in good to excellent stereoselectivities.
Keywords: Camphor, ketopinic acid, camphorsulfonic acid, proline, pyrrolidine, asymmetric organocatalysis, N-heterocyclic carbene.
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