Exacerbations of asthma are treated with oral corticosteroid medications which are associated
with various adverse effects that impact negatively on patient adherence. Historically oral corticosteroid
use has been associated with weight gain, increased appetite and dietary intake, though new
evidence suggests that these effects are not associated with short term use. Impaired response to oral
corticosteroids is also an issue in some patients due to steroid resistance. A new study suggests that
inflammometry can be used to guide patient selection for oral corticosteroid therapy to improve responses.
While oral corticosteroids remain the mainstay of treating asthma exacerbations, clinicians
should give consideration to using inflammometry for patient selection and providing guidance on the likelihood and
management of adverse effects.
Keywords: Asthma, environmental exposure, inflammation, OCS therapy, oral corticosteroid, short-term OCS.
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