A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine

Author(s): Yanling Zhao, Xiao Ma, Jiabo Wang, Xuan He, Yaming Zhang, Ye Wang, Honghong Liu, Honghui Shen, Xiaohe Xiao

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 16 , Issue 2 , 2016

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Chinese herbal medicine (CHM), an alternative and complementary medicine, has been applied in various diseases. Recently, a number of anti-liver fibrogenesis compounds exhibiting antiliver fibrosis effects have been discovered in CHM. In this review, we reviewed the published data on their anti-fibrosis effects and discussed the possible underlying mechanisms. More investigations are needed to improve the insight into therapeutic effect of CHM on liver fibrosis.

Keywords: Chinese herbal medicine, Extracellular matrix, Hepatic stellate cell, Liver fibrosis.

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Article Details

Year: 2016
Published on: 11 November, 2015
Page: [163 - 175]
Pages: 13
DOI: 10.2174/1389557515666150709121908

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