Grafting Technique with Special Emphasis on Natural Gums: Applications and Perspectives in Drug Delivery

Author(s): Rohit R. Bhosale, H.V. Gangadharappa, Afrasim Moin, D.V. Gowda, Riyaz Ali M. Osmani

Journal Name: The Natural Products Journal

Volume 5 , Issue 2 , 2015

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Graphical Abstract:


Polymers plays very important role in each portion of lives. Intentionally or unintentionally, each and every personality at present depends on polymer to get together various requirements. Even if polymers are abundant at times they cannot accomplish the bid, based on their characteristics. Advancement in polymer science is vital as they can improve the range of applications. Modification or grafting of polymers has gained better awareness for production of fresh monomers to transport enhanced polymeric materials. In short, modification is crucial to face and stand against various challenges, because it is hard to obtain new polymers. The subsequent age group looks ahead to modification of polymer as it can open up innovative promises and potentials. Sometimes, harmonization of properties is required which can be achieved via modification of polymers. Modification is needed to fetch precise properties to material which is to be modified, such as enhanced stability, compatibility, flexibility, and rigidity. Polymer modification enhances the processibility of the polymers and thus, gives an impression as new-fangled technique to overcome drawbacks associated with original polymer. Grafting techniques have proved since many years to be ground-breaking ways to modify polymers as per the requirement and still research is going on grafting of various kinds of polymers. This review highlights concept of grafting modification, techniques for grafting and applications of some grafted natural gums in drug delivery.

Keywords: Cross-linking, drug delivery, grafting, natural gums, pharmaceutical applications, physiosorption.

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Article Details

Year: 2015
Published on: 02 July, 2015
Page: [124 - 139]
Pages: 16
DOI: 10.2174/221031550502150702142228

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