Stability in Cognitive Function Over 18 Years: Prevalence and Predictors among Older Mexican Americans

Author(s): Bret T. Howrey, Mukaila A. Raji, Meredith M. Masel, M. Kristen Peek

Journal Name: Current Alzheimer Research

Volume 12 , Issue 7 , 2015

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Purpose: Numerous studies have examined the association of physical, behavioral and social factors with cognitive decline in older adults. Less attention has been placed on factors associated with long-term maintenance of intact cognition even into very old age. A greater understanding of those factors can inform the development of activities for maintaining cognitive strength. Methods: Using a sample from the Hispanic Established Populations for Epidemiologic Study of the Elderly, a population-based study of non-institutionalized Mexican Americans aged 65 and older from five Southwestern states (N = 2767), latent class mixture models were developed to identify subgroups of cognitive change over time. Results: Three distinct trajectories of cognitive change were identified and characterized as stable, slow decline and rapid decline. Compared to the rapid decline group, a higher proportion of the stable cognition group were women, had high school education, were married and attended church one or more times per week. Regular church attendance had a significant positive impact in the stable group (β = 0.64, p <0.01), the slow decline group (β = 0.84, p <0.001) and the rapid decline group (β = 2.50, p <0.001). Activity limitations had a consistently negative association with cognition in the stable, slow decline and rapid decline groups (β = -0.37, p <0.001; β = -0.85, p <0.001; and β = -1.58, p <0.001 respectively). Conclusion: Substantial heterogeneity exists in rates of cognitive decline among older Mexican Americans. Interventions targeting cognitive maintenance may benefit from increased focus on factors associated with continued social engagement.

Keywords: Aging, cognition, cognitive change, hispanic, resilience, social support, trajectory.

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Article Details

Year: 2015
Published on: 27 July, 2015
Page: [614 - 621]
Pages: 8
DOI: 10.2174/1567205012666150701102947
Price: $65

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