Peripheral artery disease (PAD) is an inflammatory disease caused by atherosclerosis. It has been demonstrated
that PAD is related to chronic inflammation. While conventional risk factors lead to the pathogenesis and progression of
PAD, the role of novel inflammatory biomarkers in relation to PAD is being increasingly recognized. The novel biomarkers
for PAD may allow for earlier screening and detection, suppression of disease progression, and development of new
therapeutic approaches. In this review, inflammatory biomarkers that should be contributory to diagnosis, prognosis, and
avenues for therapeutic challenges in PAD are summarized.